Christine E Seidman Selected Research

Glycogen Storage Disease Type IIb

3/2009	Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy.
1/2008	Reversibility of PRKAG2 glycogen-storage cardiomyopathy and electrophysiological manifestations.
5/2007	Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage.
6/2003	Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy.

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Christine E Seidman Research Topics

Disease

37	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 12/2022 - 01/2002
37	Cardiomyopathies (Cardiomyopathy) 01/2022 - 02/2002
30	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2020 - 02/2003
20	Heart Failure 01/2022 - 02/2003
18	Hypertrophy 01/2021 - 02/2002
15	Fibrosis (Cirrhosis) 12/2022 - 02/2002
11	Cardiac Arrhythmias (Arrythmia) 01/2022 - 01/2005
8	Cardiomegaly (Heart Hypertrophy) 12/2022 - 02/2002
8	Congenital Heart Defects (Congenital Heart Defect) 01/2022 - 09/2006
8	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 10/2020 - 06/2003
7	Neoplasms (Cancer) 01/2022 - 03/2007
6	Ischemia 01/2019 - 03/2007
5	Disease Progression 01/2022 - 03/2008
5	Hypertension (High Blood Pressure) 01/2022 - 06/2006
5	Familial Hypertrophic Cardiomyopathy (Cardiomyopathy, Familial Hypertrophic) 01/2017 - 01/2002
5	Polymorphic catecholergic ventricular tachycardia 08/2014 - 07/2007
4	Heart Diseases (Heart Disease) 01/2022 - 04/2005
4	Atrial Fibrillation 01/2020 - 10/2009
4	Glycogen Storage Disease Type IIb 03/2009 - 06/2003
3	Obesity 01/2022 - 04/2011
3	Heart Arrest (Cardiac Arrest) 01/2020 - 03/2009
3	Myocardial Ischemia (Ischemic Heart Diseases) 01/2019 - 01/2012
3	Myocarditis (Carditis) 10/2018 - 03/2003
3	Arrhythmogenic Right Ventricular Dysplasia (Arrhythmogenic Right Ventricular Cardiomyopathy) 02/2016 - 01/2005
3	Sudden Death 03/2009 - 12/2005
2	Stroke (Strokes) 01/2020 - 10/2018
2	familial dilated cardiomyopathy 10/2019 - 01/2010
2	Inflammation (Inflammations) 11/2018 - 10/2017
2	Cardiovascular Diseases (Cardiovascular Disease) 10/2018 - 07/2009
2	Intracranial Aneurysm (Cerebral Aneurysm) 12/2016 - 05/2009
2	Hypoxia (Hypoxemia) 10/2014 - 03/2007
2	Ventricular Tachycardia 08/2014 - 12/2013
2	Muscular Diseases (Myopathy) 01/2014 - 12/2009
2	Reperfusion Injury 01/2012 - 04/2008
2	Ventricular Dysfunction 01/2011 - 04/2009
2	Central Core Myopathy (Central Core Disease) 12/2009 - 11/2007
2	Holt-Oram syndrome 09/2006 - 06/2005
2	Atrioventricular Block 09/2003 - 02/2002
2	Wolff-Parkinson-White Syndrome (Wolf-Parkinson-White Syndrome) 06/2003 - 02/2002
2	Glycogen Storage Disease (Glycogenosis) 06/2003 - 02/2002

Drug/Important Bio-Agent (IBA)

54	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2002
8	Myosins (Myosin)IBA 10/2020 - 07/2004
8	phospholambanIBA 01/2020 - 02/2003
8	Cardiac MyosinsIBA 01/2019 - 01/2002
8	ConnectinIBA 01/2019 - 02/2012
7	CalciumIBA 01/2021 - 02/2003
7	GlycogenIBA 12/2016 - 06/2003
6	RNA (Ribonucleic Acid)IBA 01/2022 - 09/2009
6	Carrier Proteins (Binding Protein)IBA 01/2019 - 01/2002
6	DNA (Deoxyribonucleic Acid)IBA 10/2018 - 02/2004
5	Transcription Factors (Transcription Factor)IBA 01/2022 - 09/2006
5	CatecholaminesIBA 01/2021 - 03/2009
5	myosin-binding protein CIBA 01/2020 - 03/2003
5	Protein Isoforms (Isoforms)IBA 12/2016 - 11/2005
5	AMP-Activated Protein KinasesIBA 11/2005 - 02/2002
4	Myosin Heavy Chains (Myosin Heavy Chain)IBA 12/2022 - 10/2013
4	GadoliniumIBA 10/2020 - 08/2010
4	CalsequestrinIBA 08/2014 - 07/2007
4	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 03/2011 - 07/2007
3	Mitochondrial DNA (mtDNA)IBA 01/2022 - 08/2012
3	Pharmaceutical PreparationsIBA 01/2019 - 08/2014
3	Lamin Type A (Lamin A)IBA 01/2017 - 02/2008
3	Diltiazem (Cardizem)FDA LinkGeneric 01/2016 - 04/2002
3	Adenosine Triphosphate (ATP)IBA 04/2013 - 03/2007
2	AcidsIBA 12/2022 - 04/2005
2	Biological ProductsIBA 01/2021 - 09/2009
2	FilaminsIBA 01/2021 - 10/2017
2	Troponin IIBA 10/2020 - 01/2002
2	MYK-461IBA 12/2019 - 02/2016
2	LaminsIBA 10/2019 - 02/2008
2	Indicators and Reagents (Reagents)IBA 01/2019 - 09/2009
2	Lidocaine (Xylocaine)FDA LinkGeneric 11/2018 - 11/2010
2	NucleotidesIBA 01/2018 - 08/2005
2	Angiotensin IIIBA 10/2017 - 12/2013
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 10/2017 - 03/2009
2	integrin-linked kinaseIBA 10/2017 - 01/2014
2	Blood Proteins (Serum Proteins)IBA 01/2017 - 01/2005
2	Nonsense Codon (Nonsense Mutation)IBA 12/2016 - 02/2004
2	LipidsIBA 11/2016 - 04/2011
2	L-Type Calcium Channels (Dihydropyridine Receptor)IBA 01/2016 - 04/2002
2	Propranolol (Inderal)FDA LinkGeneric 08/2014 - 11/2010
2	Epinephrine (Adrenaline)FDA LinkGeneric 08/2014 - 12/2013
2	Losartan (Cozaar)FDA LinkGeneric 12/2013 - 10/2010
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2012 - 04/2008
2	Verapamil (Calan)FDA LinkGeneric 03/2011 - 11/2010
2	Procainamide (Procan)FDA LinkGeneric 11/2010 - 09/2003
2	TropomyosinIBA 01/2010 - 01/2002
2	Adenosine Triphosphatases (ATPase)IBA 01/2009 - 02/2003
2	Troponin T (Troponin T1)IBA 07/2008 - 01/2002
2	Ventricular MyosinsIBA 04/2008 - 02/2002
2	Phosphotransferases (Kinase)IBA 05/2007 - 03/2007
1	Cell Surface ReceptorsIBA 12/2022
1	lysophosphatidic acidIBA 12/2022

Therapy/Procedure

17	Therapeutics 01/2022 - 09/2003
4	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 01/2021 - 05/2008
4	Heart Transplantation (Grafting, Heart) 01/2020 - 05/2008
4	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2019 - 04/2009
2	Precision Medicine 01/2022 - 12/2019
2	Immunotherapy 01/2022 - 11/2016
2	Induced Heart Arrest (Cardioplegia) 11/2018 - 03/2015